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Manufacturing Facilities & Footage

Overview

Utide operates an integrated 6,000 m² R&D center and a 14,000 m² production facility, staffed by over 200 professionals and equipped with advanced technologies for the synthesis, purification, and isolation of peptide APIs.
The facility supports an annual production capacity of up to 1,500 kg while offering flexible custom peptide development capabilities, fully adhering to GMP standards.
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Peptide Synthesis (Upstream Manufacturing)

We specialize in Solid-Phase Peptide Synthesis (SPPS), offering a vertically integrated manufacturing platform that scales from early R&D to multi-kilogram and large-scale production.
SPPS Expertise
By leveraging advanced Fmoc- and t-Boc-based solid-phase methodologies, our proven expertise allows for the precise synthesis of challenging peptide targets, including long-chain peptides, highly hydrophobic sequences, and complex multi-disulfide-bridged cyclic peptides.

High-quality resins and optimised coupling reagents are employed to control impurity profiles from the earliest stages of synthesis.
Large-Scale and Flexible Capacity
Equipped with state-of-the-art SPPS reactors and dedicated cleavage units, we provide significant single-batch outputs to secure your large-scale supply.

Beyond mere volume, our tiered reactor configurations—ranging from pilot to industrial scales—offer the flexibility to seamlessly support your project’s journey.
Advanced Automation
Fully automated synthesis systems provide real-time control over reagent charging, critical process parameters, and washing cycles, reducing manual variability and ensuring high crude purity with consistent batch-to-batch reproducibility.

Peptide Purification & Isolation (Downstream Processing)

Our downstream processing refines crude peptides generated via SPPS to exceptional purity levels through sophisticated purification and isolation technologies
Industrial Prep-HPLC
Featuring high-pressure preparative HPLC systems, we effectively isolate and remove deletion sequences, truncated peptides, and diastereomers, consistently achieving purity levels of up to ≥99%, depending on peptide sequence characteristics
Precise Salt Exchange
We offer flexible salt-form conversions (Acetate, HCl, Phosphate, or TFA) and meticulous de-salting processes, ensuring strict control over counter-ion distribution and residual solvents to meet diverse formulation requirements
Large-Scale Lyophilization
In controlled cleanroom environments, high-capacity industrial freeze-dryers transform purified eluates into high-quality API powders with excellent solubility and physical characteristics.