Eloralintide
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Our products are intended for research use only. They are not permitted for any human or animal consumption.
Our products are intended for research use only. They are not permitted for any human or animal consumption.
Parameter
Product Number ： U3701
CAS number ： 2883634-40-8
Molecular formula ： C₂₀₁H₃₁₉N₄₉O₆₅S₂
Synthesis method ： Solid-phase chemical synthesis
Product characteristics ： White powder
Molecular weight ： 4526.2 ± 1.0
作用机制COAHPLCDetail
Eloralintide is a selective, long-acting amylin receptor agonist that functions as a selective agonist of the amylin receptor. Amylin is a hormone secreted by pancreatic β cells. By binding to the AMY1 receptor in the brain, eloralintide mimics the mechanism of action of the endogenous hormone amylin, thereby regulating appetite through enhancing satiety, delaying gastric emptying, and reducing glucagon secretion.
In addition to lowering glucagon levels, improving leptin signaling, and supporting glycemic regulation, eloralintide reduces energy intake and acts as a physiological regulator of body weight.
Research Applications:
Promoting significant weight loss.
Reducing appetite and food intake.
Improving blood sugar and lipid profiles.
Offering weekly dosing convenience.
| 项目 Items | 标准 Standard | 结果 Results | |
| 外观 Appearance | 白色或类白色粉末 White or off-white powder | 白色粉末 White powder | |
| 分子量 Molecular Ion Mass | 4526.2 ± 1.0 | 符合 Conforms | |
| 溶解度 Solubility | 在纯水中可溶解至浓度为 50 mg/ml Can be dissolved to 50 mg/ml in pure water | 符合 Conforms | |
| 酸碱度 pH | 7.0–9.0 | 7.9 | |
| 水分（K.F） Water Content (K.F) | ≤ 8.0% | 3.10% | |
| 纯度（UPLC） Purity (UPLC) | ≥ 99.0% | 99.18% | |
| 有关物质（UPLC） Related Substance (UPLC) | 总杂 Total impurities | ≤ 1.0% | 0.82% |
| 最大单一杂质 Largest individual impurity | ≤ 0.5% | 0.34% | |
| 残留溶剂（GC) Residual Solvent (GC) | 二氯甲烷 Methylene chloride | ≤ 600 ppm | 未检出 N.D |
| 乙腈 Acetonitrile | ≤ 410 ppm | 115 ppm | |
| 甲醇 Methanol | ≤ 3000 ppm | 未检出 N.D | |
| N,N-二甲基甲酰胺 N,N-Dimethylformamide | ≤ 880 ppm | 未检出 N.D | |
| 叔丁基甲醚 Isopropyl ether | ≤ 5000 ppm | 未检出 N.D | |
| 酸根离子（IC） Acid Group Ions (IC) | 三氟乙酸 TFA | ≤ 0.1% | 未检出 N.D |
| 磷酸根 PO₄³⁻ | ≤ 0.1% | 未检出 N.D | |
| 醋酸根 HAC | ≤ 0.1% | 未检出 N.D | |
| 钠离子（IC） Sodium Ion (IC) | ≤ 4.0% | 3.10% | |
| 微生物限度 Microbial Limits | 需氧微生物总数 TAMC | ≤ 1000 cfu/g | 符合 Conforms |
| 酵母和霉菌总数 TYMC | ≤ 100 cfu/g | 符合 Conforms | |
| 细菌内毒素 Bacterial Endotoxins | ≤ 10 EU/mg | 符合 Conforms | |
| 含量测定（UPLC） Assay (UPLC) | ≥ 95.0% | 98.90% | |
| 储存 Storage | 保存至密闭容器中，避光保存，储存温度为 -20±5℃ Keep in tight container, protect from light, store at a temperature of -20±5℃ | ||
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