Amycretin is a novel single-molecule peptide drug that combines two covalently linked analogues of GLP-1 and amylin, creating a dual agonist of the GLP-1 and amylin receptors. Its structure enhances both appetite regulation and metabolic control. By activating GLP-1 pathways to reduce hunger and amylin pathways to slow gastric emptying and improve satiety, amycretin supports powerful, sustained weight reduction.
Activates GLP-1 and amylin pathways to support metabolic regulation.
Helps reduce appetite and enhance satiety signals.
Slows gastric emptying to aid weight-management efforts.
Investigated for obesity and broader metabolic health applications.
项目 Items 标准 Standard 结果 Results 外观
Appearance白色或类白色粉末
White or off-white powder白色粉末
White powder分子量
Molecular Ion Mass7846.6 ± 1.0 符合
Conforms溶解度
Solubility在纯水中可溶解至浓度为 50 mg/ml
Can be dissolved to 50 mg/ml in pure water符合
Conforms酸碱度
pH7.0–9.0 8.1 水分(K.F)
Water Content (K.F)≤ 8.0% 3.50% 纯度(UPLC)
Purity (UPLC)≥ 95.0% 97.23% 有关物质(UPLC)
Related Substance (UPLC) 总杂
Total impurities≤ 5.0% 2.77% 最大单一杂质
Largest individual impurity≤2.0% 0.62% 残留溶剂(GC)
Residual Solvent (GC)二氯甲烷
Methylene chloride≤ 600 ppm 未检出
N.D乙腈
Acetonitrile≤ 410 ppm 166 ppm 甲醇
Methanol≤ 3000 ppm 未检出
N.DN,N-二甲基甲酰胺
N,N-Dimethylformamide≤ 880 ppm 未检出
N.D叔丁基甲醚
Isopropyl ether≤ 5000 ppm 未检出
N.D酸根离子(IC)
Acid Group Ions (IC) 三氟乙酸
TFA≤ 0.1% 未检出
N.D磷酸根
PO₄³⁻≤ 0.1% 未检出
N.D醋酸根
HAC≤ 0.1% 未检出
N.D钠离子(IC)
Sodium Ion (IC)≤ 4.0% 3.20% 微生物限度
Microbial Limits需氧微生物总数
TAMC≤ 1000 cfu/g 符合
Conforms酵母和霉菌总数
TYMC≤ 100 cfu/g 符合
Conforms细菌内毒素
Bacterial Endotoxins≤ 10 EU/mg 符合
Conforms含量测定(UPLC)
Assay (UPLC)≥ 90.0% 96.80% 储存
Storage保存至密闭容器中,避光保存,储存温度为 -20±5℃
Keep in tight container, protect from light, store at a temperature of -20±5℃